Investigation of Green Chemistry Approaches in the Synthesis of Pharmaceuticals

During the last two decades, research on nanoparticles and their application in various fields has been developed. Nanoparticles have exceptional electronic, catalytic, optical, magnetic, and other physical and chemical properties that are completely different from the mass of matter. Unfortunately, many organic solvents used for the synthesis of metal nanoparticles, such as thiophenol, mercaptoacetate, etc., are toxic enough to lead to environmental pollution in the synthesis of nanoparticles on a large scale. Although gold nanoparticles are considered biocompatible, using a chemical method to produce them can lead to the absorption of chemical substances on the nanoparticle and cause side effects in medical applications. The synthesis of nanoparticles using microorganisms or plants can potentially be useful for making compatible bio-nanoparticles in order to solve this important defect. The use of plant extracts for the synthesis of nanoparticles makes the synthesis process easier and its progress faster. In fact, with the extracellular synthesis of nanoparticles, there is no need to cultivate and maintain cells for the synthesis of nanoparticles. The use of plant extracts in the synthesis of metal nanoparticles, especially gold, is very promising, and so far, the synthesis of nanoparticles has been done using different plants such as cinnamon, eucalyptus black tea, and sweet root.

Investigation of Green Chemistry Approaches in the Synthesis of Pharmaceuticals Keywords:

Nanoparticles , Green chemistry , plant extract , Medicine , Organic Solvents