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Effect of Daucus carota L. extract on spermiogram factors in men with idiopathic infertility: A double‐blinded randomized clinical trial

Publish Year: 1404
Type: Journal paper
Language: English
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JR_AJP-15-2_005

Index date: 12 March 2025

Effect of Daucus carota L. extract on spermiogram factors in men with idiopathic infertility: A double‐blinded randomized clinical trial abstract

Objective: Male infertility is a common issue that affects people worldwide and presents challenges in terms of treatment. In recent times, there has been significant interest in the use of herbal remedies as a potential solution for male infertility. In this study, we aimed to assess and compare the effects of clomiphene, carrot seed, and education based on traditional Persian medicine on the sperm parameters in idiopathic male infertility.Materials and Methods: Sixty male patients experiencing infertility were randomly divided into four groups: Clomiphene, Clomiphene + Carrot, Clomiphene + Lifestyle modification, and Clomiphene + Carrot + Lifestyle modification. In the herbal group, patients received four capsules of carrot seeds, for a total of 2 g daily for 90 days. Meanwhile, subjects in the Clomiphene group were administered one tablet of clomiphene, containing 50 mg, per day for a duration of 90 days. Sperm parameters were analyzed at the beginning and end of the study.Results: After the 90-day intervention, the groups that received clomiphene combined with carrot and lifestyle interventions showed significant improvements in various sperm parameters. These improvements were statistically significant compared to the control group.Conclusion: The combination of carrot seeds along with clomiphene and education based on traditional Persian medicine was found to improve sperm parameters in cases of idiopathic male infertility without any adverse effects.

Effect of Daucus carota L. extract on spermiogram factors in men with idiopathic infertility: A double‐blinded randomized clinical trial Keywords:

Effect of Daucus carota L. extract on spermiogram factors in men with idiopathic infertility: A double‐blinded randomized clinical trial authors

Abolhasan MousaviKhorshidi

Clinical Research Development Unit [CRDU], Sayad Shirazi Hospital, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran

Ayesheh Enayati

Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Nasser Behnampour

Biostatistics Department, Faculty of Health, Golestan University of Medical Sciences, Gorgan, Iran

Emadoddin Rezaei

Counseling and Reproductive Health Research Center, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran

fatemeh kolangi

Counseling and Reproductive Health Research Center, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran