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A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS

Publish Year: 1386
Type: Conference paper
Language: English
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ISME15_424

Index date: 28 March 2007

A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS abstract

Morphological remodeling of endothelial cells induced by blood flow and pressure is considered as an adaptive response to mechanical stimuli. To determine the mechanism of response, we examined the change in the morphology of endothelial cells caused by cyclic strain. Here, we have described a new, digital image analysis method that has been adapted to evaluate fractal dimension of cellular profiles as a measure of morphological complexity. The fractal dimension seemed to be a suitable parameter for the analysis of morphological changes of endothelial cells caused by mechanical parameters such as cyclic stretch due to blood pressure.

A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS Keywords:

A STUDY OF TENSILE CYCLIC LOADING ON THE MORPHOLOGY OF CULTURED ENDOTHELIAL CELLS WITH APPLICATIONS OF FRACTAL ANALYSIS authors

Amini

Msc. student, Amirkabir University of Technology, Tehran, Iran

Tafazzoli Shadpour

Assistant professor, Amirkabir University of Technology, Tehran, Iran

Haghighipour

PhD student, Amirkabir University of Technology, Tehran, Iran

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