Effects of New Anti-Cancer Compound (2, 2-Bipyridin EthylglycinatoPd(II) Nitrate ) on the Structure of Blood Carrier Protein (Human Serum Albumin)

Human serum albumin (HSA) is the most abundant protein in systemic circulation, with HSA comprising 60% in plasma. This protein can play a dominant role on drug disposition and efficacy. HSA has a high affinity to an extraordinarily diverse range of materials, such as drugs, metabolites, fatty acids and metal ions. This protein is a single-chain 66 kDa protein, which is largely α-helical and consists of three structurally homologous domains that assemble to form a heart-shaped molecule. We have studied interaction of new synthesized component as anticancer complex. Results of the study would help us improve our complex.