Afterglow properties of CaF2:Mn nanoparticles and potential application in photodynamic therapy

Manganese doped calcium fluoride (CaF2:Mn) nanoparticles were synthesized by hydrothermalmethod. The formation and size of the nanostructure were confirmed by X-ray diffraction (XRD) patternsand scanning electron microscopy (SEM).The blue shifting of the photoluminescencespectrum of CaF2:Mnnanoparticles compared to its microstructure counterpart, is attributed to the quantum confinement effect.The excitation of CaF2:Mn nanoparticles was made using X-ray and UV light in room temperature. Since thephosphorescence spectrum of CaF2:Mn nanoparticles fairly overlaps with absorption spectrum ofphotosensitizer, it is recommended as light source for photosensitizer activation in photodynamic therapy.

Keywords:

Photodynamic therapy , Photosensitizer , Nanoparticles , Afterglow