Mapping of transcription factor binding Region of kappa casein (CSN3) gene in Iranian Bacterianus and Dromedaries camels

κ-casein is a glycosilated protein in mammalian milk that plays an essential role in the milk micelles.Control of κ-casein expression reflects this essential role, although an understanding of the mechanisms involved lags behind that of the other milk protein genes. Transcriptional regulation, a first mechanismfor controlling the development of organisms, is carried out by transcription factors binding sites (TFBSs). We determined the 5’ region for Iranian Dromedaries and bactrianus camel κ-casein gene. We also determine their regulatory TFBSs regions. This region contained 14 potential TFBSs The four of them C/EBP-α, Oct1, MGF/STAT5 and TPB have almost perfectly conserved

Keywords:

κ-casein , Bioinformatics analysis , Camels , Transcription factors