Synthesis of 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazaisowurtzitane as CL-20 explosive precursor catalyzed by CoFe2O4 magnetic nanoparticles as an efficient, recyclable and reusable catalyst under ultrasound irradiation

An efficient and convenient protocol for the synthesis of 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,9.03,11]dodecane (HBIW) by the condensation reaction of glyoxal (40% aqueous solution) and benzylamine in acetonitrile as a solvent in the presence of CuFe2O4 magnetic nanoparticles (CuFe2O4 MNPs) as a green, efficient, recyclable and reusable catalyst under ultrasound irradiation is described. The effects of solvent, catalyst, and ultrasonic irradiation power are discussed. The structure of the synthesized pure HBIW (recrystallization from ethanol) was confirmed by using various spectral techniques like IR, 1H-NMR, 13C-NMR and some of its physical properties were determined. In addition, CoFe2O4 MNPs could be reused up to six runs without any significant loss of activitiy. The prepared catalyst was characterized by SEM, XRD and FT-IR. Compared with other methods, the remarkable advantages of this method are the simple experimental procedure, simple work-up, shorter reaction times and green aspects by avoiding toxic catalysts and high yields of product.

Keywords:

HBIW , CoFe2O4 MNPs , CL-20 explosive precursor , ultrasound irradiation , reusable catalyst , cobalt ferrite