Evaluation of LamB linear and conformational epitopes on the Vibrio harveyi
Publish place: کنفرانس بین المللی مهندسی و علوم کاربردی
Publish Year: 1394
نوع سند: مقاله کنفرانسی
زبان: English
View: 485
This Paper With 15 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
ICEASCONF01_363
تاریخ نمایه سازی: 9 مرداد 1395
Abstract:
Vibriosis is one of the most serious infectious diseases in fish and shellfish. However, due to the diversity of pathogens and their complicated serotypes, the progress in vaccine development against Vibriosis has been slow. LamB proteins (or maltoporins) are a family of OMPs. It forms a betabarrel composed of three monomers and ensures the transport of maltose and maltodextrin in Gram-negative bacteria reported that recombinant Aeromonas hydrophila outer membrane protein 48, which belongs to the maltoporin group of porins, induces a protective immune response against A. hydrophila and E. tarda. There has been no other report of immunological characteristics of LamB so far. Nowadays, bioinformatics is reliably working in biology researches. It could be harnessed in vaccine plan as well as epitope mapping drives. In the present study we exploit bioinformatic tools to introduce the best regions of LamB as antigenic determinants in order to design (a) novel construct (s) as vaccine or diagnostics.
Keywords:
Authors
Elahe Dehghani
Departeman of biology, Science and Art University, Yazd, Iran
Fateme Sefid
Department of Biology, shahed University ,Tehran-Qom Express Way