A highly efficient synthesis of biologically active spirooxindole derivatives with MoO3 as a mild catalyst under solvent-free conditions
Publish place: International Conference on New Research Findings in Science, Engineering and Technology with a Focus on Need-Based Research
Publish Year: 1394
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICMRS01_121
تاریخ نمایه سازی: 8 آبان 1395
Abstract:
MoO3 as an environmentally benign nature catalyst for the multi-component efficient synthesis of biologically spirooxindole derivatives is studied. And we studied three-component, one-pot condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1, 3-dicrbonyl compounds, naphthol and 4-hydroxycumarin under thermal and solvent-free conditions in the presence of MoO3 as a mild catalyst. solvent-free conditions, short reaction times, good yields, non-toxic, in expensive, simple operational procedures, one-pot, mild, easily separated from the reaction mixture with no column chromatographic separation for the economical synthesis of these fused biologically compounds are the major advantages of this literature.
Authors
Farzaneh Mohamadpour
Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran