Sulfonic acid-functionalized silica-coated magnetic nanoparticles as a novel magnetic nanocatalyst for the synthesis of 2H-indazolo[2,1-b] phthalazine-trione derivatives under Solvent-Free Conditions

Regarding the nano chemistry’s goals, silica-coated magnetite nanoparticles (MNPs) open up new avenue to introduce an amazing and efficient system for facilitating catalyst recovery in different organic reactions. Mesoporous molecular sieves consist of an ordered array of silica tubules comprised of pores with uniform controllable diameters in the nanometer rang (2-10 nm). The new Sulfonic acid-functionalized silica-coated magnetic nanoparticles catalyst was prepared directly through the reaction of chlorosulfonic acid with silica-coated magnetic nanoparticles and used as a magnetically recyclable catalyst. Finally, the applicability of the synthesized nanocomposites was tested as heterogeneous solid catalyst for synthesis of 1-(phenyl)2H-indazolo[2,1-b] phthalazine-trione derivatives in solvent free conditions at 100 degree.

Keywords:

Mesoporous silica , 2H-indazolo[2 , 1-b] phthalazine-triones , aromatic aldehydes , dimedone , phthalhydrazide