Polybutylcyanoacrylate/cisplatin nanoparticles as a new model for delivery of drugs

Poly(alkyl cyanoacrylate) (PACA) nanosystems include various types of nanoparticles suitable to achieve in vivo drug delivery in a well controlled manner [1]. PACA nanosystemsare one of the few polymer nanoparticles used as drug carriers which have reached clinical evaluation [2]. Beside this, PACAnanosystems have been considered as potential carriers for many types of drugs; the literature is particularly abundant and includes reports on a wide range of methods for their synthesis [3].