Fabrication of Hydrogels with Controlled Porosity Using Non-Solvent Induced Phase Separation Method during Dextran Crosslinking Reaction

Porous hydrogels are of high potential for biomedical applications like tissue engineering, drug delivery, biocatalysis, etc. due to their unique properties [1]. Hydrogels based on dextran (Dex), a naturalpolysaccharide, can be used as efficient hemostatic agents. Here, adding non-solvent is examined in a crosslinking system to inducephase separation to provide porous Dex hydrogels of controllable porosity