Evaluation effect of silver nanoparticle on hepato cellular carcinoma (hcc)

Cancer is created as a result of inactivation of tumor suppressor genes and activation oncogenes as a result of genetic and epigenetic changes that tumor is created from society of cancer cells that it can be benign or malignant. It should be noted nanotechnology is one of the interdisciplinary sciences that help to development and cure the cancer. Using from metal nanoparticles for cure the cancer payattention because of side effects from usual methods cure the cancer. Researches showed that toxic effects silver nanoparticle related to with increase cell divisions, stress oxidative and apoptosis.Nanoparticles synthesized to different methods that one of them is that synthesis to green method that is this method used from bioactive materials of natural products obtained from plants or other sourcesexample bacteria’s, fungus and fermentative. Increasing natural agreement nanoparticles and natural applications is resulting of using from green method resulting, this property caused that using from these compounds to cure some illnesses for example cancer. Colon cancer or growing cancer cells is called rectum, there is problem in the end of digestive system. The most of cancers or colorectal cancers originate from association benign and mass-shaped intestinal wall cells that so-called polyp. Intestinal polyps are usually small and take long several years until be exchanged from benign stage to malignant stage or cancerous. Researches show that maybe AgNP had anticoagulant effect that it can suppress colon cancer cells also it can restrain G0/G1 phase and reduce DNA and α-apoptosissynthesis also analyzes show that using from specific biological materials encoded for synthesis , biocompatibility , stability and parts of AgNP nanoparticle into cell by SERS from point of view nanoparticles. This primary studies provide background in development cure colon cancer methods by Ag nanoparticle from green plants synthesis

Keywords:

Colon Cancer , Cancer Diagnosis , Cancer Prevention , Cancer Treatment and Management , Drugs and Cancer