Spectroscopic study and antioxidant activity of host–guest complexes of β-cyclodextrin and γ-cyclodextrin with amlodipine besylate drug

The host–guest interaction of the drug materials with cyclodextrins were improved solubility and properties without outbreak sensitive into body [1]. This point were investigated according in order to papers encapsulation drugs in cyclodextrins [2]. The aim of the study was to synthesize and characterization the host–guest complexes of amlodipine besylate drug with β-cyclodextrin (β-CD) and γ-cyclodextrin (γ-CD) which has antioxidating activity property. The intraction host–guest complex was characterized by Fourier transform infrared (FTIR) and Ultrraviolet-visible (UVvis) spectroscopics. Kinetic studies of 2,2-diphenyl-1-picrylhydrazyl (DPPH˙) cyclodextrins (CDs) complexes were done.