Effect of Elastic Resistance Training and Vitamin D on Systemic Inflammation Indices in Untrained Men: A Clinical Trial

Background: Recent studies demonstrate the ability of vitamin D to reduceinflammation and oxidative stress.Objectives: The current study aimed at examining the effect of vitamin Dsupplementation on systemic inflammation markers during an eight-week elasticresistance training (ERT) on untrained men.Materials and Methods: Forty healthy males with no experience in resistancetraining were assigned to elastic training—vitamin D (ED, n=10), elastic resistancetraining—placebo (EP, n=10), vitamin D (VD, n=10), and control (Con, n=10)groups. ERT was performed with eight exercises three times a week on nonconsecutivedays for eight weeks. Also, the subjects in the ED, VD, and EP groupsconsumed 50,000 IU vitamin D or placebo once every two weeks. Blood sampleswere collected before and 72 hours after the last session of eight weeks of ERT formeasuring concentration of tumor necrosis factor-alpha (TNF-alpha), Interleukin-6(IL-6), and C reactive protein (CRP).Results: It is found that ED elicited a significant reduction in IL6 than VD (p<0.05)and control (p<0.05). Also, there is a significant difference between EP group andVD (p<0.05) and control ones (p<0.05). However, there is no significant differencebetween ED and EP in the variables mentioned (p<0.05). Also, it was observed thatthere was no statistical significant alteration in CRP concentration between pre- andpost-training (p> 0.05).Conclusion: Finally, we can claim that the combination of elastic resistance trainingwith vitamin D did not have extra advantages in attenuation of systemicinflammatory indices when compared with the training alone.

Keywords:

Vitamin D , Resistance Training , Interleukin-6