سیویلیکا را در شبکه های اجتماعی دنبال نمایید.

A novel access to new pyrrolo[1,2-a]quinoxalines through palladiumcatalyzed multi-component reactions

Publish Year: 1397
Type: Conference paper
Language: English
View: 351

متن کامل این Paper منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل Paper (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دانلود نمایند.

Export:

Link to this Paper:

Document National Code:

IRANCC20_710

Index date: 18 May 2019

A novel access to new pyrrolo[1,2-a]quinoxalines through palladiumcatalyzed multi-component reactions abstract

Quinoxaline and its derivatives are an important class of nitrogen-containing heterocyclic compounds, show a broad spectrum of biological activities including antitumor,1 antiviral, and anti-inflammatory,2 properties. We herein present an efficient and successful approach for the synthesis of new pyrrolo[1,2-a]quinoxalines with good-to-high yields. The multi-component reaction of 3-amine substituted 2-chloroquinoxalines, benzoyl chlorides and prop-2-yn-1-amine in the presence of palladium-copper catalyst afforded functionalized pyrrolo[1,2- a]quinoxalines by amide and amine substituents at 1 and 4 positions respectively. This strategy provides the biologically active molecules in a one-pot process. All the new synthesis compounds were characterized by the analytical spectral data.

A novel access to new pyrrolo[1,2-a]quinoxalines through palladiumcatalyzed multi-component reactions authors

Sima Abbaspour

Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;

Ali Keivanloo

Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;

Mohammad Bakherad

Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;