Autoimmune polyendocrine syndrome type IIIC and ankylosing spondylitis: a case report
Publish place: Rheumatology Research، Vol: 2، Issue: 1
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_RHRE-2-1_006
تاریخ نمایه سازی: 1 خرداد 1398
Abstract:
Autoimmune polyendocrine syndrome (APS) is an autoimmune disorder defined by multiple endocrinopathies and the presence of other systemic or organ-specific autoimmunities. This case study, reports on a 46-year-old woman with confirmed idiopathic hyperparathyroidism, who was referred for inflammatory back pain. HLA-B27 positivity, recurrent anterior uveitis and radiologic findings led to ankylosing spondylitis (AS) diagnosis. By further investigations, a subclinical atrophic autoimmune thyroid disease (AITD) was also diagnosed for her in addition to a history of premature ovarian failure. According to the absence of adrenal insufficiency in addition to an AITD and systemic autoimmune disorder, APS type IIIC was the most probable diagnosis. To the best of our knowledge, this is the first case report of APS type III associated with AS.
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Authors
Ali Javinani
Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
Hamid Reza Aghaei Meybodi
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Ahmad Reza Jamshidi
Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
Farhad Gharibdoost
Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
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