Molecular iodine-catalyzed combinatorial library synthesis of 2-amino-3-cyano-4H-pyran derivatives at ambient temperature
Publish place: Journal of Communications In Catalysis، Vol: 1، Issue: 2
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_CIC-1-2_002
تاریخ نمایه سازی: 4 خرداد 1398
Abstract:
An efficient and simple synthesis of some 2-amino-3-cyano-4H-pyran derivatives was developed via the one-pot and three-component reaction of aldehydes, ethyl acetoacetate, and malononitrile in the presence of ammonium acetate at room temperature using catalytic amount of iodine. The key advantages of this method are the easy access to various substituted 2-amino-3-cyano-4H-pyran derivatives, short reaction times and high yields.
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Authors
Adeleh Moshtaghi Zonouz
Chem. Dep., Fac. Sci, Azarbaijan Shahid Madani Univ., Tabriz, Iran
Saeed Behjat
Naft research center