Abnormal Auditory Brainstem Response (ABR) Findings in a Near-Normal Hearing Child with Noonan Syndrome
Publish place: Iranian Journal of Otorhinolaryngology، Vol: 29، Issue: 1
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJOTO-29-1_009
تاریخ نمایه سازی: 12 تیر 1398
Abstract:
Introduction: Noonan syndrome (NS) is a heterogeneous genetic disease that affects many parts of the body. It was named after Dr. Jacqueline Anne Noonan, a paediatric cardiologist.Case Report: We report audiological tests and auditory brainstem response (ABR) findings in a 5-year old Malay boy with NS. Despite showing the marked signs of NS, the child could only produce a few meaningful words. Audiological tests found him to have bilateral mild conductive hearing loss at low frequencies. In ABR testing, despite having good waveform morphology, the results were atypical. Absolute latency of wave V was normal but interpeak latencies of wave’s I-V, I-II, II-III were prolonged. Interestingly, interpeak latency of waves III-V was abnormally shorter.Conclusion:Abnormal ABR results are possibly due to abnormal anatomical condition of brainstem and might contribute to speech delay.
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Authors
Bahram Jalaei
Department of Audiology, Faculty of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Mohd Normani Zakaria
Audiology Program, School of Health Sciences, University Sains Malaysia, Kelantan, Malaysia.
Dinsuhaimi Sidek
Department of Otorhinolaryngology, School of Medical Sciences, University Sains Malaysia, Kelantan, Malaysia.
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