Mccune-Albright Syndrome: A Case Report Associated with Pamidronate Therapy and Literature Review

McCune-Albright Syndrome (MAS) is a rare sporadic disease characterized by bone fibrous dysplasia, Café au lait spots and a variable association of hyperfunction endocrine disorders. There is not any certain treatment available for this syndrome, and both physical and emotional disability in these patients is still a major concern for physicians. In present report we have described a 10- year-old girl, presented with precocious puberty, multiple Café au lait  macules and fibrous dysplasia, successfully treated with pamidronate in a four-year follow-up period.

Keywords:

Children , Iran , Fibrous dysplasia , McCune-Albright syndrome , Precocious puberty