Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

Effect of valproic acid on metabolic status and endocrine system in pediatric patients with epilepsy: systematic literature review

Year: 1396
COI: JR_RCM-4-1_002
Language: EnglishView: 169
This Paper With 7 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 7 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Sona Sepahi - Iranian Academic Center for Education, Culture and Research, Mashhad University of Medical Sciences, Mashhad, Iran.
Bamdad Riahi-Zanjani - Medical Toxicology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Adel Ghorani-Azam - Medical Toxicology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract:

Introduction: Valproic acid (VPA) is an acidic compound that is commonly used as an anticonvulsant and mood-stabilizing agent in the treatment of epilepsy, mania and bipolar disorders as well as the prevention of migraine headaches. But, it can affect metabolic and endocrine system resulting in hormonal disturbances and incidence of some metabolic disease, especially in pediatric patients. In this study, we aimed to systematically review the literature wherein metabolic and endocrine effect of valproic acid has been studied in pediatric patients with epilepsy.Methods: To evaluate the relationship between VPA consumption and metabolic diseases, a systematic literature search was performed through searching for related documents in the PubMed and Scopus as two known databases using the following key terms valproic acid , metabolic disease and pediatrics in the title, keywords, and abstract of literatures. Data were then extracted and described.Result: Nearly 934 documents were collected and reviewed based on the main purpose of this study. Of the collected articles, 918 documents were excluded in several step by step processes of article selection, and only 16 relevant documents were included for further data assessment. The results showed that VPA can cause significant increase in plasma concentration of thyroid hormones and therefore increase the risk of metabolic disease in patients with epilepsy.Conclusion:The results of included documents in this review showed that VPA may induce metabolic and hormonal disturbances in pediatric patients, who were on treatment with VPA.

Keywords:

Paper COI Code

This Paper COI Code is JR_RCM-4-1_002. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/892448/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Sepahi, Sona and Riahi-Zanjani, Bamdad and Ghorani-Azam, Adel,1396,Effect of valproic acid on metabolic status and endocrine system in pediatric patients with epilepsy: systematic literature review,https://civilica.com/doc/892448

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :

  • Bauer LA. Valproic Acid. Applied clinical pharmacokinetics. New York: McGraw-Hill ...
  • Chaudhry N, Patidar Y, Puri V. Mitochondrial myopathy, encephalopathy, lactic ...
  • Labbe G, Pessayre D, Fromenty B. Drug-induced liver injury through ...
  • Price KE, Pearce RE, Garg UC, et al. Effects of ...
  • Wilffert B, Altena J, Tijink L, et al. Pharmacogenetics of ...
  • Sinclair DB, Berg M, Breault R. Valproic acid-induced pancreatitis in ...
  • Nicolai J, Gunning B, Leroy PL, et al. Acute hepatic ...
  • Mindikoglu AL, King D, Magder LS, et al. Valproic acid-associated ...
  • Wood JR, Nelson-Degrave VL, Jansen E, et al. Valproate-induced alterations ...
  • Chang P, Walker MC, Williams RS. Seizure-induced reduction in PIP3 ...
  • Belcastro V, D’Egidio C, Striano P, et al. Metabolic and ...
  • Fang J, Chen S, Tong N, et al. Metabolic syndrome ...
  • Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA ...
  • Goldberg-Stern H, Yaacobi E, Phillip M, et al. Endocrine effects ...
  • Turan MI, Cayir A, Ozden O, et al. An examination ...
  • Yilmaz U, Yilmaz TS, Akinci G, et al. The effect ...
  • Sonmez FM, Zaman D, Aksoy A, et al. The effects ...
  • Kim SH, Chung HR, Kim H, et al. Subclinical hypothyroidism ...
  • Kanemura H, Sano F, Maeda Y, et al. Valproate sodium ...
  • Verrotti A, Manco R, Agostinelli S, et al. The metabolic ...
  • Abaci A, Saygi M, Yis U, et al. Metabolic alterations ...
  • Attilakos A, Katsarou E, Prassouli A, et al. Thyroid function ...
  • Verrotti A, Laus M, Scardapane A, et al. Thyroid hormones ...
  • Rauchenzauner M, Haberlandt E, Scholl-Burgi S, et al. Effect of ...
  • Rauchenzauner M, Haberlandt E, Scholl-Burgi S, et al. Adiponectin and ...
  • Cansu A, Serdaroglu A, Camurdan O, et al. The evaluation ...
  • Vainionpaa LK, Mikkonen K, Rattya J, et al. Thyroid function ...
  • Guo C-Y, Ronen GM, Atkinson SA. Long-Term Valproate and Lamotrigine ...
  • Verrotti A, Domizio S, Angelozzi B, et al. Changes in ...
  • Komulainen T, Lodge T, Hinttala R, et al. Sodium valproate ...
  • Gokce S, Durmaz O, Celtik C, et al. Valproic acid-associated ...
  • Larsen EP, Ostergaard JR. Valproate-induced hyperammonemia in juvenile ceroid lipofuscinosis ...
  • Knights MJ, Finlay E. The effects of sodium valproate on ...
  • Dhillon N, Hogler W. Fractures and Fanconi syndrome due to ...
  • Bratton SL, Garden AL, Bohan TP, et al. A child ...
  • Verrotti A, D’Egidio C, Mohn A, et al. Antiepileptic drugs, ...
  • Verrotti A, Loiacono G, Laus M, et al. Hormonal and ...
  • Verrotti A, Agostinelli S, Parisi P, et al. Nonalcoholic fatty ...
  • Rauchenzauner M, Laimer M, Wiedmann M, et al. The novel ...
  • Ogusu N, Saruwatari J, Nakashima H, et al. Impact of ...
  • Coban D, Kurtoglu S, Akin MA, et al. Neonatal episodic ...

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 8,086
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support