Title: The effect of acacia honey-impregnated placenta membrane in second-degree burn healing inmale Wistar rat
Publish place: 20th Annual Conference and 3rd International Conference on Pathology and Laboratory Medicine
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ACPLMED20_022
تاریخ نمایه سازی: 29 تیر 1398
Abstract:
Background: The most critical kind of thermal injury is burn. Acacia honey and placenta membrane was demonstrated as a suitable natural biological wound medical care.Objectives: This study is done to investigate the effect of acacia honey-impregnated placenta membrane in second-degree burn healing in male Wistar rat..Materials and methods: For present study, 64 male Wistar rats were accidentally separated into 4 groups. Control, placenta membrane, acacia honey-impregnated placenta membrane and silver sulfadiazine-impregnated placenta membrane groups. Second-degree burn was made for all experimental Wistar rats, under the general anesthesia. To evaluation of pain in this survey we achieve RGS scale and to evaluation effect of each modality, incisional biopsy was performed from burn and adjacent non-burn regions. Data analysis was performed by using descriptive and statistical analysis manners. (P value < 0.05)Results: The RGS scale before burn damage doesn t showed considerable pain but after burn damage facial image of rat presenting intense pain. 7 day after initial medical care statistical analysis disclosed that acacia honey-impregnated placenta membrane-treated Wistar rats were considerably lower pain than three another groups. Also in this group, the number of PMNs leukocyte was considerably lower and amount of granulation tissues formation and number of fibroblasts was greater. (P value < 0.05) Conclusion: A suitable dressing for burn wound therapy and improvement of associated pain was the acacia honey-impregnated placenta membrane.
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Authors
Mehri Kalhor
PhD student of Reproductive health of Tarbiat Modarres University, Kowsar Hospital of Qazvin University of Medical Sciences
Amir Abdollah Zangivand
General Physician,Takestan Social Security Organization hospital C.E.O., Takestan, Iran
Fatemeh Samii rad
PhD student of Reproductive health of Tarbiat Modarres University, Kowsar Hospital of Qazvin University of Medical Sciences
Mohamad reza Maleki
Assistant Professor of Pediatrics School of Medicine Qazvin university of medical sciences