Peganum harmala intoxication, a case report

Publish Year:

1392

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مقاله ژورنالی

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English

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شناسه ملی سند علمی:

JR_AJP-3-3_011

تاریخ نمایه سازی: 1 مهر 1398

Abstract:

Objective: Peganum harmala (P. harmala), Espand in Persian, has small seeds and has been used in traditional medicine as emmenagogue and an abortifacient. It has various pharmacological effects such as antifungal, antibacterial, hypothermic, anticancer, antinociceptive, and reversible monoamine oxidase inhibition. Case details: This case was a 45 years old woman who ingested about 50 grams seed of P. harmala for hypermenorrhae. She suffered nausea, vomiting, dizziness, tremor, ataxia, and confusion. On physical examination, she had hypotension (BP=90/60 mmHg) with normal heart rate (60 beat/min) and impaired knee to heel test. Her consciousness was reduced without any hallucination. Her laboratory test was normal. She was discharged at good condition 18 hours later. Conclusion: In conclusion, physicians working in Iran and other regions that P. harmala is prescribed or used illegally, should know signs and symptoms of its toxicity in order to be able to deal with the emergencies, however, prognosis of these toxicity is not bad.

Authors

MohammadMoshiri
Mohammad Moshiri

Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Science, Mashhad, I. R. Iran

LeilaEtemad
Leila Etemad

Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Science, Mashhad, I. R. Iran

SoheilaJavidi
Soheila Javidi

Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Science, Mashhad, I. R. Iran

AnahitaAlizadeh
Anahita Alizadeh

Pediatrician-Toxicology Fellowship of Toxicology ward of Imam Reza Hospital of Mashhad, Mashhad University of Medical Science, Mashhad, I. R. Iran

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  • Ben Salah N, Amamou M, et al. 1986. A case ...
  • Chen Q, Chao R, et al. 2005. Antitumor and neurotoxic ...
  • el Bahri L and Chemli R. 1991. Peganum harmala L: ...
  • Frison G, Favretto D, et al. 2008. A case of ...
  • Herraiz T, Gonzalez D, et al. 2010. beta-Carboline alkaloids in ...
  • Jahaniani F, Ebrahimi SA, et al. 2005. Xanthomicrol is the ...
  • Mahmoudian M, Jalilpour H, et al. 2002 Toxicity of Peganum ...
  • Marwat SK, Rehman Fu, et al. 2011. Chapter 70 - ...
  • Pranzatelli MR and Snodgrass SR. 1987. Harmala alkaloids and related ...
  • Puzii AD, Vecherkin SS, et al. 1980. Toxicity of the ...
  • Shi CC, Chen SY, et al. 2000. Vasorelaxant effect of ...
  • Yuruktumen A, Karaduman S, et al. 2008. Syrian rue tea: ...