سیویلیکا را در شبکه های اجتماعی دنبال نمایید.

Biotic / Abiotic Stress Influences on Human Epidermal Keratinocyte Cells

Publish Year: 1398
Type: Journal paper
Language: English
View: 282

This Paper With 6 Page And PDF Format Ready To Download

Export:

Link to this Paper:

Document National Code:

JR_PCBR-2-2_002

Index date: 9 October 2019

Biotic / Abiotic Stress Influences on Human Epidermal Keratinocyte Cells abstract

Human epidermal keratinocyte cells are the first defence blocks against the aggressive agents such as pathogens and xenobiotic materials. Synthesis process of the cellular proteins can be affected by abiotic stresses (aBS like: SiO2 nanoparticles) and biotic stresses (BS like: Virus), leading to the alteration of consumed energy profiles of proteins. The consumed energy profile of each protein was calculated based on their consumed ATP during the amino acids synthesizing procedure. Cells consumed more ATP, more energy, to synthesize more proteins under BS conditions compare to aBS conditions. Our results suggested that, the cells infected by pathogens are tend to survive longer than the treated cells by xenobiotic materials. Our data analysis revealed that the most energy reduction took place under aBS conditions. So, aBS could have severe effect on energy production pathways and decrease the energy source of cells. Moreover, the results demonstrated that the complexity of cellular protein networks under aBS conditions were more than BS conditions. It seems the cellular energy reduction under aBS conditions is one of the important factors in cell death. In addition, the position of proteins in the protein network was another important factor that should be carefully considered.

Biotic / Abiotic Stress Influences on Human Epidermal Keratinocyte Cells Keywords:

Biotic / Abiotic Stress Influences on Human Epidermal Keratinocyte Cells authors

Seyed Mohammad Motevalli

National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, China

Fateme Mirzajani

Departmrnt of Nanobiotechnology, Protein Research Center, Shahid Beheshti University, G.C., Tehran, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
N. O. Fortunel, M. T. Martin, Int. J. Radiat. Biol., ...
نمایش کامل مراجع