The Relationship Between Prolactin Hormone and Polycystic Syndrome in Urmia Women

Polycystic syndrome is the most important and common endocrine disorder among women of childbearing age. Inadequate secretion of gonadotropins, FSH, LH, and prolactin can be attributed to this disease. Prolactin secretes from the lymphotrophic cells of the pituitary gland and increases its secretion by 6-fold during pregnancy.Materials and Methods: Our statistical population included 90 women with polycystic syndrome referred to Omid hospital in Urmia. 100 healthy women were selected as the control group from all subjects. Finally, data were analyzed by SPSS V.24 and Spearman correlation coefficient and T-test.Results: The mean age of the patients was 30.62 /2 2.3 years and the control group was 28.12 4 4.70 years, indicating no association with disease incidence. The mean BMI in the patient group was 27.1 ± 1.78 kg / m2. Mean serum prolactin level in patients was 21.19 12 6.12 ng / ml with a range of 10.9- 54.17 (P = 0.02) while in control group was equal to 0.09 1 1.14. Spearman s correlation coefficient between BMI and prolactin hormone showed a significant correlation with disease incidence (14 = 23 ng / ml) (CL = 1.64-3.51-OR = 95 %Conclusion: According to the results, the mutation in prolactin hormone secretion has a significant relationship with the incidence of polycystic oocyte syndrome, which can be used as a prognostic factor.

Keywords:

Prolactin , Syndrome , Polycystic oocyte , Anterior pituitary