Preparation and antibacterial effects of PVA linked quaternary ammonium salt

Microbes are living organisms such as bacteria which are the critical sources of infections. They threaten the safety and well-being of human life and the environment. In this way, antimicrobial polymers with various applications in this field are solutions to these risks. so that, polyvinyl alcohol is our choice as suitable substrate in this synthesis [1]. Polyvinyl alcohol used as an injection moulding of soluble containers for active release of detergents, eyes drop, surface coating, protective chemical-resistant gloves and different hard contact lens solution as a lubricant, and other industrial and medical, food, pharmaceutical market, packaging and textile industries and it has no odor and toxic properties. [2]. Therefore, we added quaternary ammonium salt [3]composed of morpholine and ethyl iodide to the PVA. adsorption of the positively charged quaternary ammonium compound on the negatively charged bacteria surface , disruption of the bacterial membrane by a lipophilic chain on the quaternary ammonium compound, and diffusion through the membrane leading to bacteria death.The influence of quaternary ammonium on the properties of PVA matrix was investigated by differential scanning infrared spectroscopy FT-IR,TGA, XRD, and DDM test . It was found that a structure of new polymer had an excellent antibacterial ability against of both gram negative (E.coli) and gram positive (S. aureus) bacteria.