Comparison of dexamethasone and Anti-D Immune globulin for immune thrombocytopenia purpura in children
Publish place: Reviews in Clinical Medicine، Vol: 1، Issue: 2
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_RCM-1-2_005
تاریخ نمایه سازی: 2 دی 1398
Abstract:
Different therapeutic options in children with immune thrombocytopenic purpura include observation alone, periodic treatment with corticosteroids, intravenous immunoglobulin (IVIG) or anti-D, chronic administration of immunosuppressive agents, and splenectomy.Preference of the type of therapy depends on the degree of thrombocytopenia and clinical bleeding manifestations. Dexamethasone is safe but its side effects are the main disadvantages for its usage. Anti-D is more expensive than dexamethason but the side effect is rare and not dangerous and response to treatment is assessed in approximately 3 days after infusion.
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Authors
Abdollah Banihashem
Department of Pediatrics, School of Medicine, Dr Sheikh Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Hamid Farhangi
Department of Pediatrics, School of Medicine, Dr Sheikh Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Mojtaba Mousavi Bazaz
Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Zahra Badiee
Department of Pediatrics, School of Medicine, Dr Sheikh Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
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