The prevalence of Human T-lymphotropic virus in 20 to 60 years in khoy city

Introduction and Objectives: The HTLV virus known as first human Retrovirus and it’s a part of the Oncoviridea family. An important feature of virus is geographic prevalence in our country. About 20 million of people infected in the world. This virus is a leading cause of advanced T-cell leukemia in adults. The purpose of this study was to investigate the prevalence of this virus in the population of Khoy city. Material and Methods: In this cross – sectional study, 327 individuals who referred to the Diagnostic Laboratory of Qamar Bani Hashim Hospital in Khoy city from Jan 2017 to Jan 2018, were provided with peripheral blood samples. After sampling ELISA tests were done for HTLV-1 antiviral antibodies for all samples. Positive samples confirmed by western blot test. For data analysis we used SK test (Kolmogrov-Smirnov) for non-normalization data. All of these analysis was analyzed by SPSS V.23 software. P <0.05 was considered all meaningful. Results: HTLV-1 were positive 0.6% (2/327) of the participants according to the results of ELISA. These samples confirmed by western blot testing. Conclusion: The results showed that Khoy city is a non-endemic. Also, our result showed that no significant coralation with age and sex in Khoy city. However, education are recommended to prevent the spread of the virus. Since there is no interventional therapy for HTLV-1 infection, education is the most important principle for preventing the transmission of infection to other people, especially in the blood transfusion organization, which is more at risk due to the nature of the work.

Keywords:

HTLV-1 virus , Elisa , antibody , T cells , Khoy city