Ocular Manifestations of Metabolic Syndrome

Context: Metabolic syndrome (metabolic syndrome X) is a prevalent cluster of risk factors that include high BMI, hypertension, insulinresistance and dyslipidemia. Individuals with metabolic syndrome are at an increased risk of coronary artery disease (CAD) and diabetesmellitus. Diabetes mellitus and hypertension (HTN) are associated with retinopathy and cataract. Evidence Acquisition: Bibliographical searches were performed using MEDLINE/ScienceDirect/OVID up to October 2013 using thefollowing keywords (all fields): ( metabolic syndrome OR Met syndrome ) AND [(ocular disease) OR (cataract) OR (glaucoma) OR (agerelatedmaculopathy). Results: This review explores the relationship between metabolic syndrome, including all its components, and various ocular conditionssuch as retinopathy, central retinal artery occlusion, cataract and elevated intraocular pressure. Conclusions: Today, the prevalence of metabolic syndrome is increasing, because world population life in prevalence behaviors havechanged. Its association with various ocular manifestations such as non-diabetic retinopathy, CRAO, cataract, and primary open angleglaucoma suggests that an epidemic of Met syndrome can have far-fetched ocular consequences as well.

Ocular Manifestations of Metabolic Syndrome Keywords:

Cataract , Retinal Artery Occlusion , Intraocular Pressure , Metabolic Syndrome X , Retinopathy