In-vitro efficacy of nanoparticulate calcium sodium phosphosilicate in the obstruction of dentinal tubules
Publish place: Nanomedicine Journal، Vol: 7، Issue: 1
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_NAMJ-7-1_008
تاریخ نمایه سازی: 24 دی 1398
Abstract:
Objective(s): The present study aimed to assess the in-vitro efficacy of nanoparticulate calcium sodium phosphosilicate mouthwash in the obstruction of dentinal tubules.Materials and Methods: This in-vitro, study was conducted on 120 sections obtained from extracted human premolars, which were etched with citric acid for two minutes and rinsed with distilled water. Afterwards, the sections were randomly divided into two groups (60 per each) of nanoparticulate and regular mouthwash. In addition, each group was divided into six subgroups of 10. In the nanoparticulate mouthwash subgroups, one subgroup (n=10) was evaluated using scanning electron microscopy (SEM). The remaining five subgroups were immersed in artificial saliva for different time periods and inspected using SEM. The control subgroups were exposed to regular mouthwash. The diameters and number of the open dentinal tubules were evaluated and compared using two-way analysis of variance (ANOVA).Results: The mean number of the open dentinal tubules was significantly lower in the nanoparticulate mouthwash group compared to that of the regular mouthwash group at all the time intervals (P<0.05). Moreover, the mean diameters of the open dentinal tubules were significantly smaller in the nanoparticulate mouthwash subgroups at all the time intervals (P<0.05), with the exception of four-, six-, and 12-hour intervals. Conclusion: According to the results, nanoparticulate mouthwash was more effective in the obstruction of dentinal tubules compared to regular mouthwash.
Keywords:
Dentinal tubules , Dentin hypersensitivity , Mouthwash , Nanoparticulate calcium sodium phosphosilicate , Obstruction
Authors
Shabnam Aghayan
Department of Periodontology, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Roya Asaadi
Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Abdolmajid Bayandori Moghaddam
School of Engineering Science, College of Engineering, University of Tehran, Tehran, Iran
Roya Bahmani
Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
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