Determination of Chlamydia trachomatis incidence and its role on recurrent pregnancy loss (RPL)

Background: Chlamydia trachomatis (C.T) is an obligately intracellular bacterium that is responsible for an increasing number of sexually transmitted infections in both males and females. C.T infection is the most common sexually transmitted disease (STD) in the world that can persist and also ascend in the genital tract. This intracellular and silent infection is related to some adverse pregnancy outcomes, such as miscarriage.Objective: The aim of the study was to evaluate the frequency of C.T infection among women who experienced a miscarriage.Materials and Methods: 80 female (age 17-40 yr) partners of infertile couples took pair in this study when seeking for treatment in Yazd Research and Clinical Center for Reproductive. After obtaining informed consent, women with history of ≥2 miscarriages entered the study. To achieve the objectives of this study, PCR were performed on vaginal swabs samples.Results: There was three positive sample using PCR.Conclusion: The results of this study showed that CT infection was not common among patients in the study population. However, as the population under study was not representative of Iranian women, therefore the study needs larger population for decision.

Keywords:

Chlamydia trachomatis , Miscarriage , Recurrent pregnancy loss