Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction

Sorour Ramezanpour; Zahra Bigdeli; Frank Rominger

Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction

Publish place: Asian Journal of Green Chmistry، Vol: 4، Issue: 1

Publish Year: 1399

Type: Journal paper

Language: English

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https://civilica.com/doc/1032134

Document National Code:

JR_AJGC-4-1_007

Index date: 22 July 2020

Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction abstract

In this research article, we report the synthesis of imidazo[1,2-a]pyridine derivatives through Ugi condensation in the presence of saccharin as an organocatalyst used in a three component reaction. The convenient synthetic protocol, short reaction times, easy work up, good to excellent yields and mild reaction conditions make this process both practical and attractive.

Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction Keywords:

Three-component reaction Ugi condensation Saccharin Imidazo[1 , 2-α]pyridine

Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction authors

Sorour Ramezanpour

Department of Chemistry , K. N. Toosi University of Technology, P.O. Box ۱۵۸۷۵-۴۴۱۶ Tehran, Iran

Zahra Bigdeli

Department of Chemistry , K. N. Toosi University of Technology, P.O. Box ۱۵۸۷۵-۴۴۱۶ Tehran, Iran

Frank Rominger

Organisch-Chemisches Institut der Universitaet Heidelberg, Im Neuenheimer Feld ۲۷۰, ۶۹۱۲۰ Heidelberg, Germany

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