Magnetized distilled water as a solvent: A green synthesis of pyrano[2,3‐d]pyrimidines under catalyst-free conditions

A green synthetic route to the facile one pot multicomponent synthesis of, pyrano [2,3‐d]pyrimidines have been developed using magnetized distilled water (MDW) as a green solventunder catalyst-free conditions. All reactions carried out in a short period of times and theproducts are obtained in good-to-high yields. The developed synthetic technique offersnumerous advantages including eco-friendly, clean synthesis, simplicity, low-costs, shortreaction times, high reaction yields, and easy work-up compared to the traditional syntheticmethod.

Keywords:

Pyrano [2 , 3‐d] pyrimidines , Multicomponent reaction , Catalyst-free , MDW