Relationship between family history of gastric cancer (GC) and risk of cardia and non-cardia GC in Ardabil province

Background and Aim: Recent studies have reported that family history of gastric cancer (GC) in first-degree relative increases the risk of GC. Ardabil have the highest rate of GC in Iran. Here, the aim was to determine the relationship between family history of GC and the risk of cardia and non-cardia GC in Ardabil province.Methods: In this study, ۱۹۰۰ GC patients who were referred to the endoscopy center at Imam Khomeini hospital in Ardebil province were investigated. Of them, ۱۷۸ patients had a family history of GC.Results: The mean age of patients with a family history of GC was ۷۱.۰۳. ۹.۳۶% of GC patients had a family history of GC. No significant association was found between GC family history and the risk of cardia and non-cardia GC (P> ۰.۰۵).Conclusion: No significant association was found between family history of GC and GC risk whether the tumor origin was gastric cardia or non-cardia.

Keywords:

Gastric cancer , Family history , Cardia , Non cardia , Ardabil province