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A ۴-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran

Publish place: Reviews in Clinical Medicine، Vol: 8، Issue: 2
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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لینک ثابت به این Paper:
https://civilica.com/doc/1247734

شناسه ملی سند علمی:

JR_RCM-8-2_002

تاریخ نمایه سازی: 9 مرداد 1400

Abstract:

Introduction:In the present study, we evaluated the ۴-year antimicrobial resistance trends of several nosocomial pathogens during ۲۰۱۸-۲۰۲۱ in a reffereal Mashhad hospital, Mashhad, Iran. Methods:In this study, we reviewed the data of ۷۰,۲۳۴ clinical isolates were registred Infection Control Data of Ghaem Hospital, Mashhad, Iran. The antimicrobial susceptibility testing was performed using Kirby-Bauer disk diffusion method according to clinical and laboratory standard institute (CLSI) instructions to evaluate trends of antimicrobial resistance over the times. Results: There were identified (A. baumannii: n = ۱۹,۳۷۴; K. pneumonia n = ۱۷,۲۰۶; E. coli n = ۲۳,۷۷۷; S. epidermidis: n = ۹,۸۷۷). We did not find any significant difference in changes of antimicrobial trends over the time except in minor cases . However, The pattern of antimicrobial drug resistance was gradually differed except E. coli. Conclusion: our results suggested the overall antimicrobial resistance trends was remins the same level during ۲۰۱۸-۲۰۲۱. It seems that in accessibility and stop prescribing of antibiotics can lead to decreasing antibiotic resistance rate.

Keywords:

Staphylococcus epidermidis , Escherichia coli , Klebsiella pneumonia , Acinetobacter baumanii , Antimicrobial resistance

Authors

Mahbobeh Khammar

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Sepideh Hassanzadeh

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Tara

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Malihe Siahsar

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Tahmasbi

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Masoud Keikha

Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Kiarash Ghazvini

Department of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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