The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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JR_TUMS-4-1_003

تاریخ نمایه سازی: 1 تیر 1401

Abstract:

Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade. The aging of the population and Urbanization have induced significant alters in population structure and increased the burden of non-communicable diseases, like cancers. For several years, cancer genomics studies traditionally focused on coding genes. An explosion of studies into non-coding RNAs biology has shown that they could function as tumor suppressors and oncogenic drivers in nearly all cancer types. As a result, the uncovering of the role of functional RNAs in the formation and development of cancers is a promising frontier of cancer genetics.

Authors

Helia Azodian Ghajar

Department of Medical Genetics, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Roghayeh Koohi Ortakand

Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran

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