Aggravation of chronic kidney disease by inflammatory factors; a narrative review on current concepts

Chronic kidney disease (CKD) is a common disease worldwide with several causal factors such as inflammation, as one of the most important factors. Inflammation is in turn an outcome of many factors associated to renal dysfunctions like immune dysfunction which could act as a catalyst of many other CKD risk factors. Moreover, inflammation seems to be a logical target for preventive and remedial – general and particular anti-inflammatory interventions – in patients with CKD.

Keywords:

Chronic kidney disease , Inflammatory markers , Chronic renal failure , Inflammation , Transforming growth factor beta , Interleukin ۶ , Tumor necrosis factors , chronic inflammation , Renal fibrosis