Comparative Study of Serum level of d-dimer in Patients with Cerebral Venous Thrombosis (CVT) and the Control Group

Background and Aim: Cerebral Venous Thrombosis is a potentially life- threatening condition requiring early diagnosis and treatment with clinical manifestations that are unpredictable. On the other hand, the d-dimer test is inexpensive and easy to use and can be useful in diagnosis. This study aimed to evaluate the level of d-dimer in patients with cerebral venous thrombosis conducted from March 2017 to December 2017. Materials and Methods: This case-control study was conducted in ValiasrHospital, Zanjan. Patients with cerebral venous thrombosis whose diagnosis was confirmed by MRI and MRV, were included in the study. Data was collected by taking a history and physical examination and taking blood samples for d-dimer and performing MRI and MRV. Results: In this research, 38 patients, including 35 women and 3 men with an average age of 42.00 ±9.7, were studied. The mean serum d-dimer was 905.272 ng/ml in the patients The average age and the mean d-dimer in the control group including 12 men and 18 women were 39.53  years and 243.07 ng/ml respectively. Conclusion: Regarding the fact  that the level of d-dimer in the patients group was significantly higher than the control group, it is recommended that in patients with headache and suspected of  CVT, Serum d-dimer level be measured as a diagnostic tool for the evaluation of CVT.

Comparative Study of Serum level of d-dimer in Patients with Cerebral Venous Thrombosis (CVT) and the Control Group Keywords:

Cerebral venous thrombosis , D-dimer , Magnetic resonance imaging , Magnetic resonance venography