Myofibroblasts in calcifying odontogenic cyst and dentigerous cyst
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
View: 130
This Paper With 5 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JKMU-25-5_007
تاریخ نمایه سازی: 19 دی 1401
Abstract:
Introduction:Calcifying odontogenic cyst (COC) is an odontogenic cyst that sometimes shows aggressive behavior, while dentigerous cyst (DC) always has a benign nonaggressive course. There are evidences that myofibroblasts are involved in invasion and their role in biologic behavior of odontogenic cysts has been less understood. So, the aim of the present study was to compare the role of myofibroblasts in COC and DC. Methods:In this cross-sectional study, paraffin-embedded tissue blocks of ۲۰ COCs and ۲۰ DCs were studied. Four-micron sections were prepared from tissue blocks and stained with α-SMA antibody using immunohistochemistry. Percentages of myofibroblasts were semi quantitatively classified into negative (<۵% of cells were positive), weak (۵-۵۰% cells were positive) and strong (>۵۰% of cells were positive). Percentage of myofibroblasts was compared between COC and DC groups using t-test and Chi-Square statistical tests. Results:Means of myofibroblasts percentages in COC and DC groups were respectively ۳۵±۳۳ and ۳۲±۳۰ that did not show significant difference between COC and DC groups (P=۰.۷۶). There was not any significant difference between COC and DC groups with respect to semi quantitative classification of percentage of myofibroblasts (P=۰.۶۲). Conclusion:Myofibroblasts probably do not play a significant role in different biologic behaviors of calcifying odontogenic and dentigerous cysts.
Keywords:
Authors
Negin Mansuri
Student Research Committee, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran
hamid abbaszadeh
Assistant Professor, Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Majid Sharbatdaran
Department of Pathology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
Nasrollah Saghravanian
Assistant Professor, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Hemmat Gholinia
Health Research Institute, Babol University of Medical Sciences, Babol, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :