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A Versatile and Efficient Deep Eutectic Solvent for One-pot four-component synthesis of polyhydroquinolines

Publish Year: 1401
Type: Conference paper
Language: English
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CHCONFE04_036

Index date: 9 February 2023

A Versatile and Efficient Deep Eutectic Solvent for One-pot four-component synthesis of polyhydroquinolines abstract

An efficient three-component reaction of aromatic aromatic aldehyde, 1,3- cyclohexanedione/dimedone, and ethyl acetoacetate and ammonium acetate have been developed as an atom-economic procedure catalyzed by a deep eutectic solvent [Urea][SnCl2]2. Conversion was high under optimal conditions. Other remarkable features include a much milder procedure, a shorter reaction time, a wide range of functional group tolerance, and absence of any tedious workup or purification. This procedure also avoids volatile organic and hazardous reagents/solvents and is thus an eco-friendly alternative to the existing methods.

A Versatile and Efficient Deep Eutectic Solvent for One-pot four-component synthesis of polyhydroquinolines Keywords:

A Versatile and Efficient Deep Eutectic Solvent for One-pot four-component synthesis of polyhydroquinolines authors

Masoomeh Norouzi

Department of Chemistry, Faculty of Science, Ilam University, P.O. Box ۶۹۳۱۵۵۱۶, Ilam, Iran,