Prevalence of Elevated Non-HDL Cholesterol among Patients with Diabetes in An Iranian Population

Background and Aims: Non-high density lipoprotein cholesterol (non-HDL-C), which reflects all cholesterol present in potentially atherogenic lipoprotein particles, might be a useful marker of atherosclerosis in diabetic subjects. In the present study, we evaluated the prevalence of high non-HDL-C in patients with dyslipidemia in diabetic and non-diabetic subjects following LDL-C assessment as the first goal of therapy. Materials and Methods: A data set of ۲۱۴۲ individuals was included in the study. All values of lipid profile were compared between non-diabetic and diabetic groups and the prevalence of dyslipidemia was evaluated in two groups. Results and Conclusions: According to the results, ۴۸% of patients with diabetes achieved combined LDL-C ≤۲.۵ mmol/L and non-HDL ≤۳.۳ mmol/L targets, and ۵۸.۲% of diabetic patients achieved LDL-C goal while only ۵۰.۲% attained non-HDL-C goal. Also, the results indicated that non-HDL-C significantly heightened in patients with diabetes. Therefore, non-HDL-C needs to be calculated as a routine assessment in patients with diabetes.

Keywords:

Cholesterol , Cardiovascular disease , Diabetes mellitus , Non-HDL-C , دیابت , LDL-C , بیماری قلبی عروقی