Prevalence of urinary tract infections caused by Escherichia coli andinvestigation of antibiotic resistance pattern in infants and children ofSavojbolagh city
Publish place: The First Regional Conference on Modern Achievements and Knowledge-Based Advances in Microbiology and Biotechnology
Publish Year: 1401
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
BIOTECHQ01_021
تاریخ نمایه سازی: 22 اسفند 1401
Abstract:
Introduction: Urinary tract infection (UTI) arising from Escherichia coli is one of the most importantinfectious diseases in children that causes hospitalization. The aim of this study is to determine theprevalence and antibiotic sensitivity pattern of E. coli bacteria isolated from infants and children infectedwith UTI.methods: In this descriptive-cross-sectional study, ۴۷۳ urine samples were collected from infants andchildren in a clinical diagnostic laboratory in Savojbolagh County over a period of ۶ months. The urinesample of each patient was cultured on Blood Agar and Eosin methylene blue (EMB) media. For theantibiotic sensitivity test, the disc diffusion agar method was used. For this purpose, bacteria werecultured on Mueller Hinton Agar and analyzed according to the ۲۰۲۱CLSI guideline.Results: The total number of studied urine samples was ۴۷۳. Among these, ۴۶ samples (۹.۷۲%) wereconsidered positive, of which ۳۹ (۸۴.۷۸%) were female and ۷ (۱۵.۲۲%) were male. E. coli was the causeof most UTIs in the studied group with a rate of ۷۳.۹۱%. Furthermore, ۲۹% of E. coli infections occurredin the age group ۴ - ۶ years, which is known as the high-risk group. The antibiotic sensitivity testdetermined that Nitrofurantoin with ۶۷.۳۹% had the highest sensitivity followed by Gentamicin andTobramycin (۸۵.۳۰% each). However, the highest rate of resistance was seen for cefixime with ۵۲.۹۴%.Conclusion: A severe outbreak of UTI can cause hospitalization and death in children and infants.Therefore, timely identification of the microorganism and determination of their sensitivity/resistancepattern of them will play an important role in better treatment of infections
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Authors
Mohammadreza Dehgani
۱Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran
Saman Afshar
Department of Animal Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran
Farnaz Yosefi
Department of Microbiology,Urmia Branch, Islamic Azad University, Urmia, Iran
Shahrzad Salehi
Department ofnursing, Malayer Branch, Islamic Azad University, Malayer, Iran
Javid Taghinejad
Department of Microbiology, Malekan Branch, Islamic Azad University, Malekan, Iran