The relationship between dietary micronutrients and endometriosis: A case-control study

Background: Fewer studies were on micronutrient intake in women with endometriosis, and the etiology of endometriosis remains unclear between dietary micronutrients and the risk of endometriosis. Objective: This study aimed to investigate the relationship between dietary micronutrients and the risk of endometriosis. Materials and Methods: This case-control study was conducted on ۱۵۶ women (۱۸-۴۵ yr) with and without endometriosis in the gynecology clinic of Arash hospital between May ۲۰۱۷ and May ۲۰۱۸ in Tehran, Iran. According to the laparoscopic findings, the participants were divided into ۲ groups (n = ۷۸/each), women with pelvic endometriosis as the case group and women without endometriosis pelvic as the control group. Dietary data were collected using a validated ۱۶۸-item semiquantitative food frequency questionnaire with the standard serving. A logistic regression model was used to determine the association between micronutrients and the risk of endometriosis. Results: Data analysis showed a significant relationship between micronutrients such as: potassium (OR: ۰.۷۴; CI: ۰.۵۶-۰.۹۹; p = ۰.۰۱), calcium (OR: ۰.۷۰; CI: ۰.۵۲-۰.۹۴; p = ۰.۰۰۳), and also among the vitamin C (OR: ۰.۷۰; CI: ۰.۵۲-۰.۹۴; p = ۰.۰۲), B۲ (OR: ۰.۷۳; CI: ۰.۵۵-۰.۹۸; p = ۰.۰۱), and B۱۲ (OR: ۰.۷۱; CI: ۰.۵۳-۰.۹۵; p = ۰.۰۲) with endometriosis, so those who used fewer micronutrients were at higher risk of endometriosis. Conclusion: The findings showed that the dietary intakes of calcium, potassium, vitamins B۱۲, B۲, B۶, and C are inversely related to the risk of endometriosis.

Keywords:

Diet , Endometriosis , Food questionary , Micronutrients. , رژیم غذایی , آندومتریوز , پرسشنامه , ریز مغذی ها.