Smart On-Demand and Programmed Injectable Gels for Cancer Treatment
Publish place: Multidisciplinary Cancer Investigation، Vol: 7، Issue: 1
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_MCIJO-7-1_001
تاریخ نمایه سازی: 2 خرداد 1402
Abstract:
Hydrogels are often exploited biological materials in the transfer of biomolecules such as medications, DNA, and proteins owing to apparent features including cytocompatibility and likeness to genuine human tissues. A number of biomaterials have the capacity to be injected, which allows for minimum invasion and eliminates the necessity of surgery to transplant pre-formed materials. This material is injected through the target location in a solution condition before gelling. If a stimulus generates gelation by the interaction of one or more stimuli, it can do so spontaneously. When such occurs, the substance in issue is referred to be stimuli-responsive since it reacts to its environment. In this context, we discuss the many triggers that lead to gelation and look at the various processes by which the solution becomes a gel. We also look at several trials that used these gels to treat cancer. These materials show promise for treating cancer. Injectable hydrogels and stimuli sensitive materials were the topic of several studies and reviews. To our knowledge, there hasn't been any research done on the use of smart injectable hydrogels for tumor therapy.
Keywords:
Radiation therapy , Lichen planus , Radiation induced lichen planus , Isoradiotopic response , Breast cancer
Authors
Saba Salehi
Nanotechnology Department, School of Advanced Technologies, and Tissue Engineering Department, Motamed Cancer Institute
Seyed Morteza Naghib
Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology, Tehran, Iran
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