Interaction studies of anti-breast cancer agents derived from plants with human ۱۷-beta-hydroxysteroid dehydrogenase type ۱ using molecular docking approach

Here, we used molecular docking simulations to investigate the interaction mechanism of ۸ plant-derived compounds against ۱۷β-HSD type ۱. The results showed that all selected compounds were able to interact with the receptor, and Rosmanol and Resveratrol showed the highest and lowest binding affinity, respectively.

Keywords:

Breast cancer , Plant-derived compounds , Human ۱۷-beta-hydroxysteroid dehydrogenase , Molecular docking