Determination of Bisphenol A in Bottled Mineral Water and Toy Samples by Nanoparticle Assisted Fabric Phase Sorptive Extraction (NFPSE) -High Performance Liquid Chromatography

In recent years, the presence of bisphenol A in food, drinking water, and toys is considered as a toxic compound. In this research, a Fabric-phase sorptive extraction using an organic-inorganic coating as an adsorbent was used to separate bisphenol A in different samples. The isolated bisphenol A was measured by high-performance liquid chromatography. The organic-inorganic coating was done with other methods. Optimal conditions for selecting the type of fabric and bis phenol A extraction were obtained by the central composite design in ۳ and ۵ variables according to the response surface methodology. At first, the influencing factors in NFPSE such as fabric type, number of sol-gel connections, and binding time were investigated. Also, the effects of different parameters on adsorption such as sample volume, adsorption time, solution desorption volume, desorption time and pH were examined. The calibration curve in the region (۰.۱-۱۵ ng.mL-۱) for bisphenol A was linear with a correlation coefficient of more than ۹۹%.The detection limit (LODs)andthe limit of quantificationwere ۰.۱۱ ng.mL-۱ and ۰.۳۷ ng.mL-۱ respectively.Repeatability (RSD) with three replicated experiments was ۱.۲۵%.The recovery was obtained for different samples in the range of ۹۵ to ۹۷ %. According to the obtained results, the method mentioned in this research can be introduced as a reproducible method with a high absorption capacity for bisphenol A determination in drinking water and toys.

Keywords:

Nanoparticle , Fabric phase sorptive extraction , Bisphenol A , sol-gel , Graphene oxide-polyethylene glycol