Risk Factors for In-hospital Mortality of Patients with COVID-۱۹ in Iran: A Cross-sectional Study from Six Pandemic Waves
Publish place: Evidence Based Care Journal، Vol: 13، Issue: 2
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_EBCJ-13-2_004
تاریخ نمایه سازی: 19 تیر 1402
Abstract:
Background: Demographic factors, hospital status, and comorbidities affect the mortality of patients with coronavirus disease (COVID-۱۹).Aim: This cross-sectional study was performed with aim to evaluate the mortality predictors of hospitalized COVID-۱۹ patients in northeastern Iran (Mashhad city).Method: In this retrospective study, the electronic records (demographic data, clinical variables, and comorbid conditions) of survived and non-survived hospitalized COVID-۱۹ patients were searched from March ۲۰۲۱ to March ۲۰۲۲ during six pandemic waves.Results: Analysis of ۵۹۰۹۹ hospitalized COVID-۱۹ patients showed the mean age of ۵۴.۴۷۲۲.۵ years (female: ۴۶.۹۲%). Binary logistic regression analysis showed that age, masculinity, respiratory distress, and loss of consciousness among demographic data and clinical variables significantly contributed to mortality (OR>۱, P<۰.۰۵). Diabetes, cancer, respiratory diseases, kidney diseases, and immunodeficiency diseases increased the chance of death. High SpO۲ (>۹۳) protected against death (OR<۱, P<۰.۰۵).Implications for Practice: The results of the present study revealed that the clinical outcome of COVID-۱۹ infection is highly affected by demographic, clinical, and comorbidity factors. Several factors including age, masculinity, respiratory distress, loss of consciousness, diabetes, cancer, respiratory, kidney and immunodeficiency diseases had a risk effect on COVID-۱۹ death during six pandemic waves. Also, high SpO۲ (>۹۳) was detected as a protective factor for death followed by COVID-۱۹ infection.
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Authors
Amir Bavafa
Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Elham Hosseini
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Zahra Akhoond-Ali
Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Maryam Salari
Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
Sajad Sahab Negah
Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
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