Antimicrobial effects of magnesium oxide nanoparticles and ε-poly-L-lysine against Escherichia coli O۱۵۷:H۷ and Listeria monocytogenes
Publish place: Iranian Journal of Medical Microbiology، Vol: 10، Issue: 2
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
View: 66
This Paper With 9 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJMM-10-2_004
تاریخ نمایه سازی: 16 مرداد 1402
Abstract:
Background and Aim: Microbial food contamination is of great threat to human health. Nanotechnology is considered as a promising solution to produce and develop such novel antimicrobial substances. The potential effects of nanostructured metal oxides on the reduction of such contaminants are well established. The present study was aimed to investigate the antimicrobial activities of magnesium oxide (MgO) nanoparticles and ε-poly-L-lysine against two major food borne bacteria, Escherichia coli O۱۵۷:H۷ and Listeria monocytogenes.
Materials and Methods: The minimum inhibitory concentration (MIC) values of the antimicrobial compounds, as single and in combination uses, against E. coli O۱۵۷:H۷ and L. monocytogenes were determined by resazurin reduction and micro-dilution methods, in order to calculate the fractional inhibitory concentration (FIC) index.
Results: The growing of both microorganisms was inhibited by nano MgO at the concentration of ۴.۱۰ mg/ml and at the concentrations of ۲.۰۵ and ۰.۱۳ mg/ml, ε-poly-L-lysine was effective against E. coli and L. monocytogenes, respectively. The FIC indices of ۰.۵۲ and ۰.۷۵ against E. coli and L. monocytogenes, were respectively confirmed, when the combination of both antimicrobial agents was employed.
Conclusions: The current study was revealed the inhibitory effects of both substances against E. coli and L. monocytogenes. Furthermore, a limited synergy (۰.۵-۰.۷۵) was noticed in using them, in combination.
Keywords:
Authors
Masumeh Samadi
Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Seyed Shahram Shekarforoush
Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Hamid Reza Ghaisari
Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :