Tetracycline-loaded GelMA microparticles possessing proper uniformityand stability
Publish Year: 1402
Type: Conference paper
Language: English
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Document National Code:
IRCCE11_022
Index date: 12 August 2023
Tetracycline-loaded GelMA microparticles possessing proper uniformityand stability abstract
Polypeptides and other natural polymers are increasingly being used in medicine for drug delivery, tissueengineering, and wound dressing due to their biocompatibility and ability to stimulate cellular biologicalfunctions. However, their applications are limited by their inappropriate water solubility and instability inbilogical environment. Furthermore, their tendency for degradation and denaturation in intense conditionslimits the available processing techniques inorder to produce nano/micro particles from these material. Inthe present study, stable and uniform microparticles of Tetracycline-loaded gelatin methacryloyl(GelMA) were synthesized by a facile water-in-oil technique and subsequent exposure to UV radiation.The prepared particles were followingly characterized by scanning electron microscopy and Fouriertransform infrared spectroscopy.
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