The Association of Dietary Glycemic Index with the Prevention and Treatment of COVID-۱۹: A Narrative Review
Publish place: Journal of Nutrition and Food Security، Vol: 8، Issue: 3
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JNFS-8-3_018
تاریخ نمایه سازی: 24 مرداد 1402
Abstract:
In ۲۰۱۹, a new coronavirus causing a flu-like syndrome was discovered in Chinese province of Hubei and there was a subsequent outbreak in Wuhan in December ۲۰۱۹. The severity and mortality of COVID-۱۹ are affected by several preexisting comorbidities such as type ۲ diabetes mellitus (T۲DM). A more severe complication of COVID-۱۹ in patients with diabetes could be due to the fact that hyperglycemia and insulin resistance, as important features of diabetes mellitus, are associated with a higher expression rate of angiotensin-converting enzyme-۲ (ACE-۲). ACE-۲ can act as the entry site for SARS-CoV-۲ to lung cells. Furthermore, in diabetes mellitus, increased inflammatory responses and impaired immune function are often present. Glycemic index (GI) and glycemic load (GL) are the characteristics of the diet that can affect glycemic control and insulin resistance. These two characteristics could possibly affect infections through their effect on gut microbiota composition, free radical synthesis, and mitochondrial loading. Therefore, it can be proposed that dietary GI and GL might be important factors in the development of COVID-۱۹.
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Authors
Elahe Shamshirgardi
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Iran
Asma Kazemi
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Iran
Gordon A. Ferns
Division of Medical Education, Brighton and Sussex Medical School, Brighton, England, UK
Zahra Sohrabi
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Iran
Marzieh Akbarzadeh
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Iran
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